Anaerobic transformation of halogenated aromatic

发布时间: 2015-07-01 来源:

  报告人单位:Department of Isotope Biogeochemistry,

  Helmholtz Centre for Environmental Research, Germany


  报告地点: 微生物所A102会议室

  主持人:杜文斌 研究员

  报告摘要:Bacteria have been identified using halogenated

  aromatic compounds as an electron acceptor in anaerobic respiration. The

  process is significant for the halogen element cycle and can be exploited for

  the remediation of contaminated soil and ground water. We are studying Dehalococcoides species that can be found world-wide. The cells

  can transform chlorinated benzenes, dioxins, PCBs, chlorophenols and many

  compounds more. Genome sequencing has shown that the cells were exposed to an

  evolutionary pressure for a long time leading to the development of many

  reductive dehalogenase operons in the genome. Biochemical characterization of

  the reductive dehalogenase enzymes has demonstrated the enzyme function for

  some of the dehalogenase genes and supplied evidence for a new protein-bound

  electron transport providing the energy for the organism. Proteomic and

  isotopic analyses have illuminated specific functions in the anabolism of Dehalococcoides species. The research has impact for

  biotechnological implementation in remediation but also for understanding

  microbial life in deep-marine sediments where Dehalococcoides-related Chloroflexi are highly abundant. A

  recent project revealed large parts of a single-cell genome isolated from

  marine sediments and indicates many physiological functions previously unknown.