张杰研究组

植物免疫调控与微生物识别研究组

组长：张杰 博士 研究员 博士生导师

研究方向
1.植物免疫激活的分子机制；2.病原微生物的致病机理

研究内容和意义

研究组以农作物重要病害为研究对象，研究植物免疫受体对微生物的识别和免疫激活机制，病原微生物逃逸和操控植物免疫识别和信号传导的机理，为植物抗病性改良提供靶标和策略指导。

组长介绍

课题组长：张杰研究员 博士生导师
电话：010-64806135
电子邮件：zhangjie#im.ac.cn（请将#换成@）
通讯地址：北京市朝阳区北辰西路1号院3号，
中国科学院微生物研究所
邮编：100101

学习经历
1998-2002武汉大学，学士
2002-2007中国科学院上海生命科学研究院植物生理生态研究所，博士

工作经历
2023.08- 农业微生物组学与生物技术研究室，副主任
2018/12- 中国科学院微生物研究所，研究组长
2011/11-2018/11 中国科学院微生物研究所，青年研究组长
2008/10-2011/10 北京生命科学研究所，研究助理
2007/11-2008/09 美国Columbia University/Baylor College of Medicine，访问学者

获奖情况
2019年 国家优秀青年科学基金
2017年 中国科学院青年创新促进会优秀会员
2013年 中国科学院青年创新促进会会员
2010年 北京市博士后杰出英才
学术兼职
2019/07-至今 中国植生学会植物微生物分子互作专业委员会副主任
2019/07-至今 中国植生学会青年工作委员会委员
2017/10-至今 中国植物保护学会青年工作委员会委员 

研究队伍（请将#换成@）

工作人员
孙丽璠 助理研究员 sunlf#im.ac.cn
杨晓彤 实习研究员 yangxt#im.ac.cn

在读研究生
硕士生 赵培辰2016级
硕士生 韩婷婷2017级
硕士生 叶子芩2018级
硕士生 武晓云2019级
硕士生 汪昱伶2020级
已培养学生
硕士生 杨帆 2013级
硕士生 邢海影 2014级
硕士生 王凯伦 2015级

发表论文（# indicates first author; * indicates corresponding author）

1. L Sun, J Qin, W Rong, Hao Ni, H Guo andJ Zhang*, Cellophane surface-induced gene, VdCSIN1, regulates hyphopodium formation and pathogenesis via cAMP-mediated signaling inVerticillium dahliae,Molecular Plant Pathology, 2019,20, 323-333. 
2. J Zhang,S Dong, W Wang, J Zhao, X Chen, H Guo, C he, Z He, Z Kang, Y Li, Y Peng, G Wang, X Zhou, Y Wang*, and J Zhou*, Plant immunity and sustainable control of pests in China: Advances, opportunities and challenges (in Chinese),Scientia Sinica Vitae, 2019, 49, 1-29. 
3. S Mei, Z Wang,J Zhang*,and W Rong*, First report of leaf blight on Stenotaphrum secundatum caused by Nigrospora osmanthi in China,Plant Disease Notes, 2019,103，1783-1783. 
4. F Gao, B Zhang, J Zhao, JHuang, P Jia, S Wang, JZhang, JZhou, and HGuo, Deacetylation of chitin oligomers increases virulence in soil-borne fungal pathogens,Nature Plants, 2019, 5, 1167-1176 
5. JQin, KWang, LSun, HXing, SWang, LLi, SChen, H Guo* andJ Zhang*,The plant specific transcription factors CBP60g and SARD1 are targeted by aVerticilliumsecretory protein VdSCP41 to modulate immunity,eLife,2018, doi: 10.7554/eLife.34902.  
6. J Qin^#, X Zhou^#, L Sun, K Wang, F Yang, H Liao, W Rong, J Yin, H Chen, X Chen* andJie Zhang*, TheXanthomonaseffector XopK harbours E3 ubiquitin-ligase activity that is required for virulence,New Phytologist, 2018, 220, 219-231. 
7. X Zhou, L Jia, H Wang, P Zhao, W Wang, N Liu, S Song, Y Wu, L Su,J Zhang, N Zhong*, and G Xia*, The potato transcription factor StbZIP61 regulates dynamic biosynthesis of salicylic acid in defense againstPhytophthora infestansinfection,The Plant Journal, 2018, 95, 1055-1068. 
8. L Sun, J Qin, K Wang,J Zhang*, Expansion of pathogen recognition specificity in plants using pattern recognition receptors and artificially designed decoys,Science China Life Sciences, 2017, 9, 797-805. 
9. S Wang, H Xing, C Hua, H Guo*andJ Zhang*,An improved single-step cloning strategy simplifies theAgrobacterium tumefaciens-mediated transformation (ATMT)-based gene disruption method forVerticillium dahliae,Phytopathology, 2016, 106, 645-652. 
10. Y Li^#, L Han^#, H Wang,J Zhang, S Sun, D Feng, C Yang,Y Sun, N Zhong*, and G Xia*,The thioredoxin GbNRX1 plays a crucial role in homeostasis of apoplastic reactive oxygen species in response to Verticillium dahliae infection in cotton,Plant Physiology, 2016, 170, 2392-2406. 
11. SKang, F Yang, L Li, HChen, S Chen, andJZhang*,TheArabidopsistranscription factor BRASSINOSTEROID INSENSITIVE1-ETHYL METHANESULFONATE-SUPPRESSOR1 is a direct substrate of MITOGEN-ACTIVATED PROTEIN KINASE6 and regulates immunity,Plant Physiology, 2015, 167, 1076-1086. 
12. F Feng, F Yang, W Rong, X Wu,J Zhang, S Chen, C He*, and J Zhou*, AXanthomonasuridine 5’-monophosphate transferase inhibits plant immune kinases,Nature, 2012, 485, 114-118. 
13. Z Zhang, Y Wu, M Gao,J Zhang, Q Kong, Y Liu, H Ba, J Zhou, and Y Zhang*, Disruption of PAMP-induced MAP kinase cascade by aPseudomonas syringaeeffector activates plant immunity mediated by the NB-LRR protein SUMM2,Cell Host Microbe, 2012, 11, 253-263. 
14. T Xiang, N Zong,J Zhang, J Chen, M Chen andJ Zhou*,BAK1 is not a target of thePseudomonas syringaeeffector AvrPto,Molecular Plant Microbe Interactions, 2011,24, 100-107. 
15. J Zhang*, and J Zhou, Plant immunity triggered by microbial molecular signatures,Molecular Plant, 2010, 3, 783-793. 
16. J Zhang^#, W Li^#, T Xiang, Z Liu, K Laluk, X Ding, Y Zou, M Gao, X Zhang, S Chen, Tesfaye Mengiste, Yuelin Zhang, and Jian-min Zhou*, Receptor-like cytoplasmic kinases integrate signaling from multiple plant immune receptors and are targeted by aPseudomonas syringaeeffector,Cell Host Microbe, 2010, 7, 290-301. 
17. J Zhang^#, H Lu^#, X Li, Y Li, H Cui, C Wen, X Tang, Z Su, and J Zhou*, Effector-triggered and pathogen-associated molecular pattern–triggered immunity differentially contribute to basal resistance toPseudomonas syringae,Molecular Plant Microbe Interactions, 2010, 23, 940-948. 
18. L Chen^#, H Wang^#,J Zhang, L Gu, N Huang, J Zhou, and J Chai*, Structural basis for the catalytic mechanism of phosphothreonine lyase,Nature Structural Molecular Biology, 2008, 15, 101-102. 
19. T Xiang^#, N Zong^#, Y Zou^#, Y Wu,J Zhang, W Xing, Y Li, X Tang, L Zhu, J Chai, andJ Zhou*,Pseudomonas syringaeeffector AvrPto blocks innate immunity by targeting receptor kinases,Current Biology, 2008, 18, 74-80. 
20. J Zhang, F Shao, Y Li, H Cui, Li Chen, H Li, Y Zou, C Long, L Lan, J Chai, S Chen, X Tang, and J Zhou*, APseudomonas syringaeeffector inactivates MAPKs to suppress PAMP-induced immunity in plants,Cell Host Microbe,2007, 1, 175-185. 
21. H Li^#, H Xu^#, Y Zhou^#,J Zhang, C Long, S Li, S Chen, J Zhou, and F Shao*, The phosphothreonine lyase activity of a bacterial type III effector family,Science, 2007,315, 1000-1003. 
22. X Li, H Lin, W Zhang, Y Zou,J Zhang, X Tang, and J Zhou*, Flagellin induces innate immunity in nonhost interactions that is suppressed byPseudomonas syringaeeffectors,Proceedings of the National Academy of Sciences, 2005, 102, 12990-12995.