光遗传学与抗病免疫
2023-2024 德国维尔茨堡大学, 博士后
2024-至今 中国科学院微生物研究所,研究员
我们的研究是建立在微生物、植物、动物等交叉学科的基础上,从微生物以及植物中发掘并开发通用型以及功能定制化光遗传学工具。结合合成生物学等技术方法利用光遗传学探索植物生长发育机理以及研究植物抗病机理。
1. M. Ding, S. Gao,Non-invasive optogenetic stimulation of distinct stress responses in plants. Nature Research Briefing (2024).
2. M. Ding#, Y. Zhou#, D. Becker#, S. Yang#, M. Krischke, S. Scherzer, J. Yu-Strzelczyk, M. J. Mueller, R. Hedrich*, G. Nagel*, S. Gao*, K. R. Konrad*, Probing plant signal processing optogenetically by two channelrhodopsins. Nature 633,872–877 (2024).
3. D. Graus, K. Li, J.M. Rathje, M. Ding, M. Krischke, M.J. Muller, T.A. Cuin, K.A.S. Al-Rasheid, S. Scherzer, I. Marten, K.R. Konrad*, and R. Hedrich*, Tobacco leaf tissue rapidly detoxifies direct salt loads without activation of calcium and SOS signaling. The New phytologist 237, 217-231 (2022).
4. S. Huang#, M. Ding#, M. R. G. Roelfsema, I. Dreyer, S. Scherzer, K. A. S. Al-Rasheid, S. Gao, G. Nagel, R. Hedrich*, K. R. Konrad*, Optogenetic control of the guard cell membrane potential and stomatal movement by the light-gated anion channel GtACR1. Science advances 7, eabg4619 (2021). (Co-first author).
5. Y. Zhou#, M. Ding#, S. Gao#*, J. Yu-Strzelczyk#, M. Krischke, X. Duan, J. Leide, M. Riederer, M. J. Mueller, R. Hedrich, K. R. Konrad*, G. Nagel*, Optogenetic control of plant growth by a microbial rhodopsin. Nature plants 7, 144-151 (2021). (Co-first author).
6. Y. Zhou, M. Ding, G. Nagel, K. R. Konrad, S. Gao*, Advances and prospects of rhodopsin-based optogenetics in plant research. Plant physiology 187, 572-589 (2021).
7. Y. Zhou, M. Ding, X. Duan, K. R. Konrad, G. Nagel, S. Gao*, Extending the Anion Channelrhodopsin-Based Toolbox for Plant Optogenetics. Membranes 11, (2021).
8. M. Ding#, H. Dong#, Y. Xue, S. Su, Y. Wu, S. Li, H. Liu, H. Li, J. Han, X. Shan*, Y. Yuan*, Transcriptomic analysis reveals somatic embryogenesis-associated signaling pathways and gene expression regulation in maize (Zea mays L.). Plant molecular biology 104, 647-663 (2020).
9. B. Liu, S. Su, Y. Wu, Y. Li, X. Shan, S. Li, H. Liu, H. Dong, M. Ding, J. Han, Y. Yuan, Histological and transcript analyses of intact somatic embryos in an elite maize (Zea mays L.) inbred line Y423. Plant Physiol Bioch 92, 81-91 (2015).